Apoquel, or oclacitinib, is a commonly prescribed medicine for treating allergic and atopic dermatitis in dogs. Its efficacy in relieving irritation and inflammation makes it a preferred medication among veterinarians.
The following article provides a detailed review of Apoquel, including dose instructions and probable adverse effects. Let’s get started with our article without wasting any time.
What is Apoquel and Its Uses for Dogs?
Apoquel is an immunomodulator that suppresses Janus kinase (JAK) enzymes, which play an essential role in the immune system’s response. By targeting these enzymes, Apoquel can rapidly reduce the itching and inflammation caused by allergies in dogs.
Apoquel may also be beneficial in treating other skin diseases in dogs. However, it has not received FDA approval to treat any additional disorders. Using Apoquel for purposes other than allergic dermatitis in dogs is considered off-label usage.
In dogs, Apoquel is frequently recommended for the following reasons;
- Allergic Dermatitis: A common skin ailment brought on by various allergens, including pollen, food, and fleas.
- Atopic Dermatitis: An inflammatory, long-term skin condition that is frequently inherited.
How Much Apoquel Can You Give to Your Dog?
Apoquel’s effectiveness and safety rely heavily on appropriate dosage. Apoquel can be given with or without meals.
- The suggested starting dose is 0.4 to 0.6 mg/kg (0.18 – 0.27 mg/lb) of the dog’s body weight, given orally twice daily for up to 14 days.
- For maintenance therapy, the same dose should be given once daily.
Always check your veterinarian for specific dosing instructions and watch for any adverse effects on your dog.
Apoquel Dosing Chart For Dogs
Dog’s Weight |
Apoquel Dosage |
6.6 – 9.9 lbs |
1.8 – 2.7 mg |
10 – 14.9 lbs |
3.6 – 5.4 mg |
15 – 19.9 lbs |
5.4 – 7.2 mg |
20 – 29.9 lbs |
7.2 – 10.8 mg |
30 – 44.9 lbs |
10.8 – 16.2 mg |
45 – 59.9 lbs |
16.2 – 21.6 mg |
60 – 89.9 lbs |
21.6 – 32.4 mg |
90 – 129.9 lbs |
32.4 – 46.8 mg |
Over 130 lbs |
Adjust according to the veterinarian’s advice |
Is Apouel Safe For Dogs?
Typically, Apoquel is safe for dogs, but adverse effects can occur. Less common but serious side effects of Apoquel are;
- Increased susceptibility to infections: Dogs treated with Apoquel can be more exposed to bacterial and fungal infections as a result of the immunomodulatory effects of the drug.
- Neoplasia development: There have been reports of an increase in the incidence of certain kinds of cancer, but a definite causal link has yet to be demonstrated.
- Blood abnormalities: Variations in blood cell count, such as leukopenia (low white blood cell count) or anemia.
However, Apoquel is not suggested for small dogs less than 12 months old, with severe infections, during breeding, pregnancy, or breastfeeding.
What are the Safety Precautions and Considerations Before Giving Apoquel to Your Dog?
Giving an Apoquel to your dog can be safe and effective. However, it’s essential to take several safety precautions and considerations into account:
1. Consult with a Veterinarian
Always consult a veterinarian before beginning Apoquel. They can determine whether the drug is appropriate for your dog’s condition and prescribe the correct dosage.
Consulting a veterinarian is one of the best things a pet owner should do before administering Apoquel to their dogs. They will suggest the correct dosage that is suitable for their condition.
2. Check for Pre-existing Conditions
Apoquel may not be appropriate for dogs with certain pre-existing conditions, such as significant infections or a history of cancer, because it affects the immune system.
Your veterinarian will consider these variables to determine whether Apoquel is safe and appropriate for your dog.
3. Immune System Considerations
Apoquel suppresses the immune system, making your dog more prone to illness. Because of the affected immune system, your dog can be affected by other significant infections.
Regular check-ups are necessary to keep your large dog healthy while using this medicine and maintain a healthy immune system.
4. Monitor for Side Effects
Common side effects include nausea, diarrhea, lethargy, and anorexia. Monitor your dog regularly and report any unpleasant reactions.
Keep a close eye on your dog and immediately report any negative behaviors to your veterinarian. Your veterinarian will suggest the perfect solution for these common side effects.
5. Long-term Use
Consult your veterinarian about the consequences of long-term usage. While Apoquel can benefit chronic diseases, long-term usage requires frequent monitoring for potential adverse effects and general health.
Thus, giving the drug exactly as prescribed guarantees that your dog gets the therapeutic benefits while lowering risk.
What are the better alternatives to Apoquel?
Alternatives for dogs that cannot tolerate or do not respond well to Apoquel include:
- Cytopoint (Lokivetmab): A monoclonal antibody treatment that explicitly targets cytokines that cause itching.
- Corticosteroids: They have a higher chance of long-term adverse effects yet are effective for short-term relief.
- Antihistamines: These are commonly used to treat minor allergies. However, they may need to be more effective.
Frequently Asked Questions
1. Is Apoquel safe for long-term use?
Apoquel can be used for long-term treatment if monitored by a veterinarian. Regular check-ups are important to monitor the dog’s health.
2. How is Apoquel administered to dogs?
Apoquel is administered orally in the form of tablets, as prescribed by a veterinarian.
3. Can Apoquel be given with other medications?
Yes, Apoquel can be given with other medications, but always consult your veterinarian to ensure there are no adverse interactions.
4. What are the common side effects of Apoquel in dogs?
Common side effects include vomiting, diarrhea, and lethargy. If severe side effects occur, contact your veterinarian.
5. How quickly does Apoquel work?
Apoquel typically begins to relieve itching within 4 hours and controls it effectively within 24 hours.
Wrapping Up
Apoquel is a highly effective treatment for allergic and atopic dermatitis in dogs. Understanding the proper dose and awareness of any adverse effects can help ensure your dog benefits from this medicine. For any specific advice, always consult your veterinarian to address any health issues your pet may have.
